NOVEMBER 6th 2023

13:00-14:30 REGISTRATION AND POSTER SET UP

14:30-15:00 WELCOME

15:00 LACTOFERRIN AND ITS PEPTIDES: CHARACTERIZATION AND CONTROL QUALITY

VOGEL Hans J

Department of Biological Sciences, University of Calgary, Canada

Lactoferrin, functional protein-protein interactions and release of bioactive peptides

JUAREZ PEREZ Victor

Alaxia SAS, Lyon, France

Pharma Grade Lactoferrin. A Regulatory Perspective

16:30-17:00 COFFEE BREAK

17:00 LACTOFERRIN AND ITS PEPTIDES: CHARACTERIZATION AND CONTROL QUALITY

SHARMA Sujata

Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India

C-lobe of Lactoferrin: Understanding the full potential of the half-molecule of a moonlighting protein

ROSA Luigi

Department of Public Health and Infectious Diseases, University of Rome La Sapienza, Rome, Italy

Influence of sialic acid of lactoferrin in its antibacterial, antiviral and antiinflammatory activities

OBERČKAL Jernej

Arhel Ltd, Pod lipami, Komenda, Slovenia

Isolation of lactoferrin from acidic whey: increasing the capacity of the cation exchange chromatographic extraction on CIMmultus® SO3 monolithic column

19:00 WELCOME PARTY

NOVEMBER 7th 2023

09:00 LACTOFERRIN AND ITS IMMUNOMODULATING ACTIVITY

CUTONE Antimo

Department of Biosciences and Territory, University of Molise, Pesche, Italy

Iron saturation drives lactoferrin effects on HIV Tat-mediated oxidative stress and neurotoxicity

ABAD Inés
Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain
Lactoferrin reverses the intestinal alterations caused by antibiotic treatment in a murine model

BHATNAGAR Sonika
Netaji Subhas University of Technology, Sector-3, Dwarka, Delhi, India
Lactoferrin peptides as human neutrophil elastase inhibitors: basis of anti-inflammatory action?

10:30-11:00 COFFEE BREAK

11:00 LACTOFERRIN RECEPTORS AND LOCALIZATION

SCHRYVERS Anthony B.

Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Canada

Lactoferrin – bacterial interactions: how prevalent are lactoferrin receptors in Gram-negative bacteria?

CHAN Clement

Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Canada

Evaluating bacterial transferrin/lactoferrin binding protein-based vaccine antigens using a mutant Neisseria meningitidis strain expressing an exogenous transferrin/lactoferrin receptor

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13:00-15:00 LUNCH

15:00 LACTOFERRIN: IRON AND INFLAMMATORY HOMEOSTASIS

VALENTI Piera

Department of Public Health and Infectious Diseases, University of Rome La Sapienza, Rome, Italy

The efficacy of a novel lactoferrin mixture in restoring iron and inflammatory homeostasis disorders in anemic patients

CHRISTOFI Maria-Dolores

Department of Nursing, School of Health Sciences, Cyprus University of Technology, Cyprus

The effectiveness of oral bovine Lactoferrin compared to oral iron supplementation in patients with a low hemoglobin profile: A systematic review and meta-analysis of randomized clinical trials.

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16:30-17:00 COFFEE BREAK

17:00 LACTOFERRIN: CELL PROLIFERATION, DIFFERENTIATION AND NEURODEVELOPMENT

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NOVEMBER 8th 2023

09:00 LACTOFERRIN AND INFECTIOUS DISEASES

LONNERDAL Bo

Department of Nutrition, University of California, Davis, USA

Antiviral activities of different lactoferrins

PIACENTINI Roberta

Department of Biochemistry, Sapienza University, Rome, Italy

Lactoferrin inhibition of the complex formation between ACE2 receptor and SARS-CoV-2 recognition binding domain

COSTANZA Gaetana

Unit of Virology, Policlinic of Tor Vergata, Rome, Italy

Lactoferrin assumption in vaccinated subjects infected by SARS-CoV-2 influenced time length of negativization (November 2021-March 2022)

10:30-11:00 COFFEE BREAK

11:00 LACTOFERRIN AND INFECTIOUS DISEASES

WANG Jianhua

Gene Engineering Laboratory, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijng, China

Branched chimeric lactoferricin and its antimicrobial properties.

OCHOA TEAM
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Effect of lactoferrin on biofilm formation of multidrug resistant uropathogenic Escherichia coli

RUIZ-MAZÓN Lucero
Centro de Investigación y de Estudios Avanzados del IPN, CdMx, Mexico
Effect of bovine lactoferrin on biofilm formation of Mannheimia Haemolytica A2

LEON-SICAIROS Nidia

Laboratorio de Biologia Celular, Facultad de Medicina, Universidad Autonoma de Sinaloa, Mexico

Lactoferrin and derived peptides avoid glucose assimilation in fungal pathogens

PANDIT Surabhi

Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India

Lactoferrin in mucormycosis treatment: sinergistic analysis

13:00-15:00 LUNCH

15:00 BREAST MILK AND INFANT FORMULA

OCHOA TEAM

Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru

Comparison of lactoferrin concentrations in milk from mothers in Lima and the Peruvian Amazon

16:00 MILK AND COLOSTRUM VERSUS LACTOFERRIN

ROSA Luigi

Department of Public Health and Infectious Diseases, University of Rome La Sapienza, Rome, Italy

Antibacterial, antiinvasive and antiinflammatory activities of bovine lactoferrin extracted from colostrum and milk versus colostrum

BUEY Berta

Departamento de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain

Lactoferrin enriched whey and buttermilk based formulas prevent neuroinflammation and serotonergic alterations in a murine model of DSS-induced ulcerative colitis

RUTHERFURD-MARKWICK Kay.

College of Health, Massey University East Precinct Albany Expressway, Auckland, New Zealand

In Vivo effects of IDP® on antibody responses to the influenza vaccine

16:30-17:00 COFFEE BREAK

17:00 LACTOFERRIN FUNCTIONS FROM IN VITRO TO IN VIVO STUDIES

– PEDIATRICS

OCHOA Theresa J.

Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru

Role of lactoferrin on pediatric infections.

OTSUKI Katsufumi

Department of Obstetrics and Gynecology, Showa University Koto Toyosu Hospital, Tokyo, Japan

Lactoferrin functions from studies in Reproductive medicine, Perinatology and Pediatrics

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NOVEMBER 9th 2023

09:00-13:00 WALKING TOUR TO DISCOVER CARAVAGGIO, THE ROMAN BAROQUE AND RENAISSANCE

15:00 LACTOFERRIN FUNCTIONS FROM IN VITRO TO IN VIVO STUDIES

• GASTROENTEROLOGY

GRILC Blaž

Faculty of Pharmacy, Department of Pharmaceutical Technology, University of Ljubljana, Ljubljana, Slovenia

Development of enteric-coated pellets containing lactoferrin for local delivery into the small intestine

• UROLOGY

PAESANO Rosalba

Microbo s.r.l., Rome, Italy

Lactoferrin in the treatment of cystitis in in vitro and in vivo studies

• GYNECOLOGY

WAS Kamila
Department of Microbiology, The Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland
Microbiological study of lactoferrin’s impact on the growth of clinical isolates of vaginal lactobacilli. Implications for the use of lactoferrin to treat bacterial vaginosis

GELBFISH Gary
Metrodora Therapeutics LLC, New York, USA
Clinical development of intravaginal lactoferrin for treatment and prevention of recurrence of bacterial vaginosis

OTSUKI Katsufumi

Department of Obstetrics and Gynecology, Showa University Koto Toyosu Hospital, Tokyo, Japan

Effect of lactoferrin in 30 patients with refractory bacterial vaginosis

• DERMATOLOGY
  
  

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• BONE REGENERATION

CORNISH Jillian

Department of Medicine, University of Auckland, Auckland, New Zealand

Lactoferrin enhances the treatment of bone infections

• ONCOLOGY
  

MA Jian
Central South University, Changsha, China
Lactoferrin is involved in the tumorigenesis of prostate cancer

16:30-17:00 COFFEE BREAK

17:00 LACTOFERRIN FUNCTIONS FROM IN VITRO TO IN VIVO STUDIES

• NEUROLOGY

WANG Bing

Xiamen University, China

Molecular characterization of lactoferrin receptor in response to dietary lactoferrin supplementation improves neurodevelopment and cognitive function in piglets.

IANIRO Giusi

Department of Biosciences and Territory, University of Molise, Pesche, Italy

The effect of lactoferrin in a rotenone-induced Parkinson model

SIZONENKO Stéphane

Geneva University Hospital, Switzerland

Neuroprotective role of lactoferrin during brain development and injury through lifespan

20:30 GALA DINNER

NOVEMBER 10th 2023

09:00 NOVEL USES: ITALIAN AND INTERNATIONAL EXPERIENCES

VASILYEV Vadim

Institute of Experimental Medicine Saint-Petersburg, Russia

Human holo-lactoferrin/oleic acid complex: efficient suppressor of tumor cells proliferation

DECEMBRINO Nunzia

AOU Policlinico “Rodolico-San Marco”, University of Catania, Italy

Oral administration of lactoferrin reduces febrile neutropenia and favors gut eubiosis in onchohaematological children undergoing induction chemotherapy

GONZÁLEZ Luis

Instituto de Medicina Tropical Alexander von Humboldt, Lima, Peru

Oral lactoferrin  administration does not impact the diversity or composition of the infant gut microbiota in a Peruvian cohort

10:30-11:00 COFFEE BREAK

11:00 NOVEL USES: ITALIAN AND INTERNATIONAL EXPERIENCES

JUAREZ PEREZ Victor

laxia SAS, 30 rue Edouard Nieuport, 69008 Lyon, France

Safety and tolerability of inhaled lactoferrin in healthy volunteers.

SANCHES Eduardo Farias

Geneva University Hospital, Switzerland

Bovine lactoferrin as adjiuvant strategy for boosting neuroprotection induced by hypothermia after brain hypoxia-ischemia in rats

POLLIO Giuditta

AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

Lactoferrin efficacy in treating hyperferritinemia in patients suffering from pathologies unrelated and related to hemochromatosis.

SOKOLOV Alexey

Institute of Experimental Medicine Saint-Petersburg, Russia

Lactoferrin prevents halogenative and oxidative stress in rats with experimental hyperglycemia