History
December 1, 2022 2023-01-24 11:03History
The International Conferences on Lactoferrin Structure, Function and Applications are held every two years: in Hawaii (USA) in 1993 and 1995, Le Touquet (France) 1997, Sapporo (Japan) 1999, Calgary (Canada) 2001, Capri (Italy) 2003, Honolulu (USA) 2005, Nice (France) 2007, Beijing (China) 2009, Mazatlán (Mexico) 2011, Rome (Italy) 2013, Nagoya (Japan) 2015, Rome (Italy) 2017, Lima (Perú) 2019 and Beijing (China) 2021.
Since 1960’s, when the protein was first isolated both from human and bovine milk, the number of publications on lactoferrin structures, biochemical properties and biological functions is significantly increasing.
At the end of 2022 the total number of international papers concerning different activities of human and bovine Lactoferrin in native and recombinant form is around 9,600 with a high increase in the last years.
In the past three years, more than 90 papers have been published concerning the role of lactoferrin and its peptides against SARS-CoV-2, of which 60 papers are reviews or commentary. It is notable to underline that only few papers have unveiled the molecular mechanisms in in vitro study and the efficacy toward COVID-19 in clinical studies. Of note, concerning the clinical studies, only 4 reported the efficacy of Lf against COVID-19, while in the other 7, Lf has been tested as biomarker of a disease.
